At What Temperature Does Food Begin To Spoil. At what temperature does milk spoil? The usda’s suggestion is to not eat meat that has skilled greater than 4 hours of cumulative time between 40° and 140° f.

In hot weather, the food will enter the danger zone much more quickly. When food enters the danger zone, germs may grow quickly and cause food poisoning. Milk can be refrigerated safely for 2 weeks after opening.